A glycosylation reaction is a chemical reaction where a sugar moiety is attached to another saccharide, protein or lipid via a glycosidic bond. This reaction can produce two different anomers, known as the a- and b-anomer. During her studies, Line Juul-Madsen investigated methods to enhance the selectivity of the glycosylation reaction, aiming to preferentially produce one anomer over the other. Additionally, she explored how to make it easier to perform the glycosylation reaction on a large scale by eliminating the need for time-consuming column chromatography.

The PhD degree was completed at the Department of Chemistry, Faculty of Natural Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Friday 4th of October 2024 at 1.15 pm.
Place: Building 1532, room 116, Auditorium G1, Department of Mathematics, Ny Munkegade 120, Aarhus University, 8000 Aarhus.
Title of dissertation: Towards Scaleable Batch Production of Oligosaccharides
Contact information: Line Juul-Madsen, e-mail: ljm@chem.au.dk, tel.: +45 31159420

Members of the assessment committee:
Associate Professor Christian Marcus Pedersen, Department of Chemistry, Copenhagen University, Denmark

Professor Antony Fairbanks, University of Christchurch, Canterbury, New Zealand

Associate Professor Steen Uttrup Pedersen, Department of Chemistry, Aarhus University (chair)

Main supervisor:
Associate Professor Henrik Helligsø Jensen, Department of Chemistry, Aarhus University

Language: The PhD dissertation will be defended in English

The defence is public.
The PhD thesis is available for reading at the Graduate School of Natural Sciences/GSNS, Ny Munkegade 120, building 1521, 8000 Aarhus C.