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Analysis of membranes and membrane proteins – new ways of targeting membrane proteins

PhD defence, Monday, 31st May 2021. Lisbeth Thorup Ravnkilde.

2021.05.31 | Karen Konradi

Lisbeth Thorup Ravnkilde

During the 3 years of PhD studies, Lisbeth Thorup Ravnkilde has research the Glucagon receptor, a membrane protein target for treatment of type II diabetes, along with promising membrane mimics called Nanodiscs. Around 60% of current drug targets are membrane proteins, highlighting the need for understanding the membrane and its effect on the membrane proteins. These new research findings contribute to a deeper understanding of the effect the membrane induces on the membrane proteins thereby enabling new ways of target membrane proteins and treating diseases such as type II diabetes.

The PhD study was completed at department of Chemistry, Faculty of Natural Sciences, Aarhus University and at Novo Nordisk A/S, Måløv.

This summary was prepared by the PhD student.

The PhD defence will be held online. To receive a link to the event, please send an e-mail to lrk@chem.au.dk
Title of PhD thesis: Computational modelling of the Glucagon receptor and Nanodiscs

Contact information: Lisbeth Thorup Ravnkilde, e-mail: lrk@chem.au.dk, tel.: +45 42647476

Members of the assessment committee:

Senior department manager Lars Olsen, Novozymes A/S, Denmark

Prof. Lars Schäfer, Center for Theoretical Chemistry, Ruhr University, Germany

Ass. Prof Tobias Weidner (chairman), Department of Chemistry, Aarhus University, Denmark

Main supervisor:
Prof. Birgit Schiøtt, Department of Chemistry, Aarhus University, Denmark

Co-supervisor:
Principal scientist Jesper Ferkinghoff-Borg, Novo Nordisk A/S, Denmark

Language: The PhD dissertation will be defended in English

The defence is public.
Due to the coronavirus situation, the PhD thesis will not be available for reading at the offices of the PhD administration. Instead, interested parties may send an e-mail to gradschool.nat@au.dk to receive a digital copy of the PhD thesis. Please note, it may in certain cases be necessary to make an individual arrangement to read the PhD thesis.

PhD defence
16882 / i43