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Controlling the conformation of a DNA-grafted polymer

PhD defence, Tuesday 25 May 2021, Mette Riis Bakke

2021.05.25 | Mie Meulengracht Christensen

Mette Riis Bakke

During her studies, Mette Riis Bakke has designed and utilized DNA origami nanostructures mainly to investigate and manipulate polymers. Her research is building on previous work in the research group in which DNA-grafted conjugated polymers have been developed and been positioned on DNA origami through the DNA handles. Mette has used this combination of the DNA origami technique with the DNA-grafted polymers allowed for the determination of the energy transfer efficiency of a conjugated polymer. Furthermore, a DNA origami platform was built for tying a knot on such a DNA-grafted polymer, thereby illustrating complex nanoscale manipulation.

The research presented in the PhD dissertation shows just a few examples of the multitude of opportunities that the combination of DNA origami structures and DNA-grafted polymers offer.

The PhD degree was completed at the Interdisciplinary Nanoscience Center (iNANO), Faculty of Natural Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Tuesday, May 25 2021 at 15.15
Place: The PhD defence will be held at Aarhus University. 
To receive a link to the event, please send an e-mail to Ole Aalund Mandrup, oam@inano.au.dk
Title of dissertation: Nanoscale Manipulation of Polymers
Contact information: Mette Riis Bakke, e-mail: m.bakke@inano.au.dk
Members of the assessment committee:
Professor, Dr. Barbara Sacca, Center of Medical Biotechnology (ZMB), University of Duisburg-Essen, Germany
Professor Poul Nielsen, Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Denmark
Professor Duncan Sutherland, iNANO, Aarhus University, Denmark (chair)
Main supervisor:
Professor Kurt V. Gothelf, iNANO, Aarhus University
Language: The PhD dissertation will be defended in English

The defence is public.

Due to the coronavirus situation, the PhD thesis will not be available for reading at the offices of the PhD administration. Instead, interested parties may send an e-mail to gradschool.nat@au.dk to receive a digital copy of the PhD thesis. Please note, it may in certain cases be necessary to make an individual arrangement to read the PhD thesis.

PhD defence
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