Fantastic Fluorination Methods and How to Find Them
PhD defence, Wednesday 25 January 2023, Oliver Raae Gedde
During his Ph.D. studies, Oliver Raae Gedde, has been developing new fluorination methods using gaseous building blocks. The tri- and difluoromethyl groups are often observed in pharmaceuticals and agrochemicals, hence methods for their synthetic installation is of high importance for these industries. Oliver together with other members of the Skrydstrup group have developed two new techniques. One for the synthesis of trifluoroacetophenones and another for the formation of aromatic difluoromethyl compounds. A new chemical, ICF2D, was developed and proven to be the state-of-the-art reagent for the installation of deuterium labeled difluoromethyl groups. Oliver also initiated a project on the dimerization of two CO2 molecules using molecular bimetallic gold or cobalt complexes as electrocatalysts.
The PhD degree was completed at the Interdisciplinary Nanoscience Center (iNANO), Faculty of Natural Sceinces, Aarhus University.
This summary was prepared by the PhD student.
Time: Wednesday, 25/01-2023, at 13:15
Place: Building 1593, room 012, iNANO Aud., iNANO, Aarhus Universitet, Gustav Wieds Vejs 14, 8000 Aarhus C.
Title of thesis: Development of Fluorination Reactions using Gaseous Building Blocks
Contact information: Oliver Raae Gedde firstname.lastname@example.org
Members of the assessment committee:
Professor David John Procter, Department of Chemistry, University of Manchester, England
Professor Robert Madsen, Department of Chemistry, Technical University of Denmark (DTU), Denmark
Professor Alexander N. Zelikin (chair), Department of Chemistry, Aarhus University, Denmark
Professor Troels Skrydstrup, Department of Chemistry, Aarhus University, Denmark
Language: The defence will be held in English
The defence is public.
The PhD thesis is available for reading at the Graduate School of Natural Sciences/GSNS,
Jens Baggesens Vej 53, building 5221, 8200 Aarhus N