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High-throughput screening model for systematic investigation of the cellular response to topographical nanostructures

PhD defence, Thursday, 20 January 2022, Christian Thorup Karlsson.

2022.01.20 | Mie Meulengracht Christensen

Christian Thorup Karlsson

The ability to control cellular behavior by designing their environment at the nanometer length scale is predicted to have tremendous impact on future tissue engineering, stem cell therapy and cell culture work. During his studies, Christian Karlsson researched mammalian cellular responses to topographical titanium nanostructures by a newly developed model called the Nanotopographical Screening Array. The model represents 60 fields of unique topographies of titanium nanopillars with systematically varying diameter and interpillar distance.

The new findings will contribute to the future unravelling of the complex interactions and mechanisms between artificially created materials and mammalian cells, which will be used in future tailor-made biomedical surfaces.

The PhD study received financial support by the Danish SDC office and was carried out as a collaboration between Interdisciplinary Nanoscience Center (iNANO), Faculty of Natural Sciences, Aarhus University, and National Center for Nanoscience and Technology, University of Chinese Academy of Sciences.

The PhD study was completed at Interdisciplinary Nanoscience Center (iNANO), Faculty of Natural Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Thursday, 20 January 2022 at 14.15
Place: The PhD defence will be held online. To receive a link to the event, please send an e-mail to Senior Researcher Morten Foss, Foss@inano.au.dk
Title of PhD thesis: High-throughput screening model for systematic investigation of the cellular response to topographical nanostructures
Contact information: Christian Thorup Karlsson, e-mail: karlsson@inano.au.dk
Members of the assessment committee:
Professor, Dr. Klaus D. Jandt, Otto Schott Institute of Materials Research (OSIM), Friedrich Schiller University Jena, Germany
Associate Professor Peter Fojan, Department of Materials and Production, Aalborg University, Denmark
Associate Professor Ken Howard (chairman), Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Denmark
Main supervisor:
Senior Researcher Morten Foss, iNANO, Aarhus University, Denmark
Language: The PhD dissertation will be defended in English

The defence is public.

 The PhD thesis is available for reading at the Graduate School of Natural Sciences/GSNS, Katrinebjergvej 89F, building 5132, 8200 Aarhus N.

PhD defence
16882 / i43