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Identification and selective targeting of antigens on cells with new therapeutics

PhD defence, Thursday, 26 January 2023. Anne Selch Tvilum.

Anne S. Tvilum

During her PhD studies, Anne Tvilum, researched how specific antigens present on e.g. bacterial cells could be targeted using selective proteins known as antibody drug conjugates (ADC). By using the ADC, infections in the human body can be identified and cured with no of very few side effects compared to traditional broad spectrum antibiotic treatments. This technique was also used to identify and distinguish specific cell types, so called “painted cells”, from normal cells followed by communication to the painted cells. The research has contributed to a new way of treating bacterial infections on implants and in the development of a new communication route to targeted cells.

The PhD study was completed at Department of Chemistry, Faculty of Natural Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Thursday, 26th January 2023 at 09:00
Place: Building 1531,room 215, Aarhus University, Ny Munkegade 116, 8000 Aarhus C
Title of PhD thesis: Expanding the use of Antibody Drug Conjugates

Contact information: Anne Tvilum, e-mail: tvilum@chem.au.dk, tel.: +45 29 21 26 58

Members of the assessment committee:
Professor Karsten Haupt, Université de Technologie de Compiègne, Alliance Sorbonne University, France

Professor Sotirios Kampranis, Department of Plant and Environmental Science, Copenhagen University, Denmark 

Associate Professor Tobias Weidner (chair), Department of Chemistry, Aarhus University, Denmark

Main supervisor:
Professor Alexander N. Zelikin, Interdisciplinary Nanoscience Center (iNano), Aarhus University, Denmark

Language: The PhD dissertation will be defended in English

The defence is public.
The PhD thesis is available for reading at the Graduate School of Natural Sciences/GSNS,

Jens Baggesens Vej 53, building 5221, 8200 Aarhus N.

16882 / i43