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Pushing the limits of 3D nanostructures

PhD defence, Monday 13 February 2023, Mads Koch Skaanning

Mads Koch Skaanning

During his PhD studies, Mads Koch Skaanning investigated the development and utilization of artificial nucleic acids. Artificial nucleic acids are of great interest, because the introduction of chemical modifications in the backbone of DNA and RNA can alter their biological properties, thereby expanding the potential applications of oligonucleotides. Mads Koch Skaanning studied the application of acyclic threoninol nucleic acid (aTNA) as a potential oligonucleotide therapeutic and tool for building nanostructures. His studies led, among other things, to the development of very small 3D nanostructures with great stability under physiological conditions.

The PhD study was completed at Interdisciplinary Nanoscience Center (iNANO), Faculty of Natural Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Monday, 13 February 2023 at 13:15
Place: Building 1532, room 112 Aud G2, Department of Mathematic, Aarhus University, Ny Munkegade, 8000, Aarhus.
Title of PhD thesis: Diving into the world of nucleic acid chemistry: an exploration of artificial nucleic acids and the origin of life

Contact information: Mads Koch Skaanning, e-mail: mskaanning@inano.au.dk, tel.: +45 26 22 65 39

Members of the assessment committee:

Professor Annemieke Madder, Department of Organic Chemistry, Ghent University, Belgium

Professor Jesper Wengel, Department of Physics and Chemistry, University of Southern Denmark, Denmark

Associate Professor Elena Ferapontova (chair), Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Denmark

Main supervisor:
Professor Kurt V. Gothelf, Department of Chemistry and Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Denmark

Language: The PhD dissertation will be defended in English

The defence is public.
The PhD thesis is available for reading at the Graduate School of Natural Sciences/GSNS,

Jens Baggesens Vej 53, building 5221, 8200 Aarhus N.

16882 / i43