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Study group on single-particle Cryo Electron Microscopy

: 1 ECTS per semester

Course Parameters:

Language: English 

Level of course: PhD Course

Time of year: all year

No. of contact hours: 1 hour every second week

Capacity limit: 30 people


Objectives of the course:

This course aims to study the method Cryo Electron Microscopy and discuss novel research within the field of single particle CryoEM. Through the course the student will gain a detailed knowledge of the method, the different applications and a general knowledge about single particle studies. 


Learning outcomes:

  • Identify, present and discuss scientific texts
  • Obtain a thorough understanding of the theoretical aspect of the CryoEM method and its applications
  • Understand both relevance and challenges of the technique in regards to the study of single-particle CryoEM
  • Constructively read scientific text with relation to the project


Compulsory program:

Reading relevant chapter of the textbook as well as participating actively in the discussion and give small presentations when relevant. 


Course content

The study group will be based on the book “Single-particle Cryo-EM of Biological Macromolecules” by Glaser, Nogales and Chiu (2021) and recent papers. Participants must read/prepare the relevant pages for each meeting.

The course will take place every second week, with an in dept discussion about chapters/articles where a chairperson leads the discussion. Estimated 3-4 hours of preparation is needed in advance for every 1 hour meeting. 



  • General knowledge of molecular biology and a general idea about the technique
  • Interest in single-particle CryoEM and in obtaining a deeper understanding


Name of course responsible:

Charlott Stock 


Type of course:

Study group with presentations and group discussions



Primarily “Single-particle Cryo-EM of Biological Macromolecules” by Glaser, Nogales and Chiu (2021) and relevant articles 


Course homepage:



Course assessment:

Active participation in discussions at the meetings and admissible presentations



Department of Molecular Biology and Genetics, Aarhus University


Specielt comments:




Fridays at 11-12 in uneven weeks 



Currently on zoom


Deadline for registration is 31 January and 31 August for Spring and Autumn semester, respectively. Information regarding admission will be sent out no later than 2 days after.

For registration: Please send an e-mail to Charlott Stock at cs@mbg.au.dk

If you have any questions, please contact Charlott Stock at above mentioned e-mail address. 

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